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ORIGINAL ARTICLE
Year : 2017  |  Volume : 23  |  Issue : 1  |  Page : 54-58

Cord blood lipid profile in relation to anthropometric measures of newborns


1 Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt
2 Department of Clinical and Chemical Pathology, National Research Institute, Cairo, Egypt
3 Department of Pediatrics, Ministry of Health Hospitals, Cairo, Egypt

Correspondence Address:
Nermin Ramy
New Children Hospital, Abu El Rish, Cairo University Hospitals, Ali Basha Ebrahim, PO Box 11562, Zip code: +02, Cairo
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/kamj.kamj_5_17

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Background Elevated serum lipid is a contributing factor in cardiac diseases. Exposure to stress in utero may affect lipid metabolism and anthropometric measures at birth. Objective The aim of the study was to assess cord blood lipid profile of newborns and its possible effect on newborn body measurements. Patients and methods This prospective cross-sectional study was conducted on 100 newborns. They were divided into three groups: small for gestational age (SGA), appropriate for gestational age (AGA), and large for gestational age (LGA) groups. Maternal data were recorded, and BMI was calculated. Cord blood lipids, namely, total cholesterol, triglycerides (TGL), low-density lipoproteins (LDL), and high-density lipoproteins, were assessed. Results Mean levels of TGL and LDL were significantly higher in the SGA group compared with the AGA group, and significantly higher in the AGA group compared with the LGA group, whereas mean total cholesterol levels were significantly higher in the SGA group, with no difference between AGA and LGA groups. There was a strong negative correlation between TGL and each of birth weight, abdominal circumference, and ponderal index. The same was reported for LDL. Furthermore, maternal BMI did not affect neonatal lipids. Conclusion Variation in lipid profile at birth can affect anthropometric measures of the newborn.


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