• Users Online: 408
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2018  |  Volume : 24  |  Issue : 1  |  Page : 19-25

Vitamin D status in patients with type-2 diabetes mellitus in Riyadh City, Saudi Arabia

Department of Internal Medicine, Faculty of Medicine, Benha University, Banha; Department of Internal Medicine, Rafa Medical Center, Riyadh City, Egypt

Correspondence Address:
Mysara M Mogahed
Department of Internal Medicine, Faculty of Medicine, Benha University, Banha
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/kamj.kamj_30_17

Rights and Permissions

Background Type-2 diabetes mellitus (T2DM) is a progressive and chronic disease characterized by both β-cell dysfunction and increased insulin resistance. Vitamin D is a crucial factor in the development of T2DM because it is necessary for normal insulin secretion. Despite ample sunshine, vitamin D deficiency is common in the Middle East. Objective To report the vitamin D status and its impact on the people in Riyadh City, Saudi Arabia, with T2DM. Patients and methods The study was carried out on 100 patients of 31–79 years old with T2DM. According to their vitamin D status, they were classified into three groups: group 1 (deficient, vitamin D: <20 ng/ml), group 2 (insufficient, vitamin D: 20–30 ng/ml), and group 3 (normal, vitamin D: >30 ng/ml). All were subjected to history taking, clinical examination, and assessment of fasting blood samples of serum concentrations of 25-hydroxy vitamin D [s-25(OH)D], blood glucose, glycated hemoglobin, lipid profile, liver enzymes (alanine transaminase and aspartate transaminase), urea and creatinine. Results Inadequate vitamin D level was observed in 80% of the participants, with a mean s-25(OH)D of 18.3±10.9 ng/ml. S-25(OH)D correlated negatively with fasting blood sugar (FBS) (P=0.008), with cholesterol and low-density lipoprotein (P=0.012 and 0.003, respectively). The low vitamin D status was strongly associated with poor glycemic control (P=0.001) and in females (P=0.002). There was no significant association between s-25(OH)D level and different age groups. Conclusion There is an overwhelming prevalence of vitamin D deficiency in our sample of Saudi diabetic patients. Association of low vitamin D status with poor glycemic control and atherogenic lipid profile suggests a role of vitamin D in the control of T2DM and dyslipidemia and the importance of early detection of its deficiency and vitamin D supplementation.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded303    
    Comments [Add]    
    Cited by others 1    

Recommend this journal